New Posts
More Recent Posts

The dynamic functional connectivity of the brain and the fMRI: an overview of analytical strategies

Resting-state functional magnetic resonance imaging (fMRI) is a method of functional brain imaging (i.e., the measurement of the aspect of a brain area by images) that can be used to evaluate regional interactions that occur when a subject is resting. The fMRI has highlighted the rich structure of brain activity in absence of a task or stimulus. […]

Continue reading


The diseases of the synaptic vesicles open the way to a new group of neurometabolic diseases

The Inborn Errors of Metabolism (IEM) have normally been considered as the result of errors at the genetic level affecting the biochemical pathways of small molecules such as the neurotransmitters glycine, glutamate, GABA, biogenic amines, etc. The altered concentration of such molecules in the Cerebrospinal Fluid (CSF) have always been used as a diagnostic biomarker […]

Continue reading


Central Serotonin Receptor 7 constitutes a potential therapeutic target for Rett Syndrome

Rett syndrome is a neurodevelopment disorder affecting around 1 out of 10,000 girls, usually due to de novo mutations in the X-located gene MECP2. It is a complex disorder, both clinically and at a molecular level, and is typically characterized by a neurodevelopment regression starting at age 6 to 18 months after a normal early […]

Continue reading