Scientists have the need to develop and choose the best biological models to understand the basis of the diseases in preclinical studies. Currently, animals and monolayer cell cultures (2D cultures) are widely spread as reference models. Anyway, these models are not completely reliable when it is necessary to comprehend some key events of the development […]
Author Archives: Luca Maggioni
38 posts published by Luca Maggioni
Does a relation exist between brain GABA levels and psychiatric disorders?
Gamma-aminobutyric acid (GABA) plays a key role in many physiological processes of brain. It is present in one third of synapses in the central nervous system, and modulates neurotransmission via GABAergic interneurons. Although the involvement of GABA in psychiatric disorders is well-known, understanding its role in their etiology is very difficult. In order to achieve […]
DHA: a key omega-3 fatty acid in children brain development
Docosahexaenoic acid (DHA) is a long-chain omega-3 fatty acid naturally present in cold water fatty fish, and in maternal breast milk. DHA is also available in fish oil, in algal supplements, and in fortified milk and eggs. Although DHA can be synthesized from short-chain precursor a-linolenic acid, diet-assumed DHA accumulates more efficiently in erythrocytes, breast […]
Page 8 of 8
