The Rett syndrome (RTT) and the Autism Spectrum Disorder (ASD) are neurodevelopmental disorders which, although presenting different symptoms and evolution, are linked by a common factor: mutations in the same gene, called MECP2. But the answers on how and why the same gene could have a key role in the development of both diseases have […]
24 posts found
Brain networks
The big challenge of the brain circuits
One of the most complicated and fascinating challenges for the neuroscientists is how to link the architecture, the wiring and the electric messages of the neuronal circuits to our behavior and emotions. To date, the desire of understanding this correspondence is simply unrealistic: the reason lies in numbers. 302: is the number of neurons that […]
The dynamic functional connectivity of the brain and the fMRI: an overview of analytical strategies
Resting-state functional magnetic resonance imaging (fMRI) is a method of functional brain imaging (i.e., the measurement of the aspect of a brain area by images) that can be used to evaluate regional interactions that occur when a subject is resting. The fMRI has highlighted the rich structure of brain activity in absence of a task or stimulus. […]
RETT SYNDROME: FROM THE PATIENT TO THE LABORATORY, A ROUND TRIP
Updating Day in the research carried out on Rett Syndrome by the HSJD and its collaborators.
Central Serotonin Receptor 7 constitutes a potential therapeutic target for Rett Syndrome
Rett syndrome is a neurodevelopment disorder affecting around 1 out of 10,000 girls, usually due to de novo mutations in the X-located gene MECP2. It is a complex disorder, both clinically and at a molecular level, and is typically characterized by a neurodevelopment regression starting at age 6 to 18 months after a normal early […]
Page 1 of 5
