24 posts found

Cholinergic neurotransmission and the developing brain

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What do you know about acetylcholine?  What about its role in the developing brain?   Are there diseases of the central nervous system due to abnormal cholinergic transmission in paediatrics? Our current knowledge about disorders of neurotransmission in children is focused on transmitters such as dopamine, serotonin or GABA. By contrast little is known about the […]

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Serotonin and cortical architecture

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The neurotransmitters sculpt the brain Serotonin is an abundant neurotransmitter in the brain. During development, serotonin regulates processes such as neuronal migration and dendrite differentiation through some particular 5HT receptors. Abnormal serotoninergic neurotransmission during early periods of life may disrupt the construction of  cortical circuits and contribute to neurologic and neuropsychiatric disorders.   The human […]

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New insights on Human Connectome

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Resting state fMRI provides powerful information on neuron connectivity at an individual cellular level. An increasing number of publications in the last decade have highlighted a growing interest, not only in the anatomical connections between neurons but also in the functional and metabolical connections between them. This work studying the connection to and from a single neuron, […]

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