Cellular Neurochemistry

Share

The nervous system is made up of different cell populations. These diverse cells interact to create a functioning brain. Understanding this cellular diversity and how they relate to each other is one of the major challenges of modern neuroscience.  The biochemical and molecular specialization of the nervous cells defines function at different developmental stages. In other words, the micro-anatomy of the brain provides the basis for its biochemical and molecular properties, which can vary depending on the age of the child. In this section you will find information about the major components of the nervous system and how they change during neurodevelopment and in relation with different neuropaediatric disorders.

-Neurons

-Glia

-Blood-brain barriers

dibuix elisenda

23 posts published about Cellular neurochemistry

Epilepsia y metabolismo sináptico

Share

Los conocimientos que la neurociencia básica y el neurometabolismo están aportando a la epilepsia pediátrica son rápidamente crecientes. Estos avances son especialmente notables en el área específica de los mecanismos de comunicación sináptica. Existe, no obstante, una desconexión entre estos avances y una visión que los integre de manera global y en la práctica clínico-terapéutica. […]

Continue reading


Glutamatergic receptor disorders in children

Share

What do you know about glutamatergic transmission? What kind of neuropaediatric disorders are related to glutamatergic receptor mutations? What kind of symptoms could be associated with abnormal glutamatergic transmission?     Glutamate is the most abundant excitatory neurotransmitter in the nervous system and it plays a key role in long-term potentiation (LTP). LTP is involved […]

Continue reading


Official launch of the CGB network

Share

“Connecting The Growing Brain” http://www.connectingthegrowingbrain.com. Network of paediatric neurologists and basic researchers that aims to understand the developing brain through synaptic communication. Today we are pleased to announce the official launch of the network “Connecting the growing brain” (CGB). We are a group of pediatric neurologists and basic researchers working together to understand how dysfunctions […]

Continue reading


Abnormal Gabaergic transmission in Rett syndrome

Share

Neurons may remain immature concerning GABAergic neurotransmission in Rett syndrome Abnormal expression of cation chloride cotransporters has been found in the cerebrospinal fluid of patients with Rett syndrome (RTT). This finding suggest an abnormal GABaergic transmission and neuronal maturation.  According to these results, neurons of RTT patients could remain “immature” regarding GABA excitability, as it […]

Continue reading


Page 4 of 5