2 entradas encontradas

Glutamatergic receptor disorders in children

Share

What do you know about glutamatergic transmission? What kind of neuropaediatric disorders are related to glutamatergic receptor mutations? What kind of symptoms could be associated with abnormal glutamatergic transmission?     Glutamate is the most abundant excitatory neurotransmitter in the nervous system and it plays a key role in long-term potentiation (LTP). LTP is involved […]

Continuar leyendo


Neurotransmisión gabaérgica anómala en el síndrome de Rett

Share

Neurons may remain immature concerning GABAergic neurotransmission in Rett syndrome Abnormal expression of cation chloride cotransporters has been found in the cerebrospinal fluid of patients with Rett syndrome (RTT). This finding suggest an abnormal GABaergic transmission and neuronal maturation.  According to these results, neurons of RTT patients could remain “immature” regarding GABA excitability, as it […]

Continuar leyendo