3 posts found

MR imaging detects metabolic alterations in brain of ADHD subjects

The attention deficit/hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder in children and adolescents. It may persist until the adult age in 30-50% of cases. Among the characteristic traits of the ADHD, there can be found the propensity for risk-taking and the inclination to the abuse of substances and to the gambling. The subjects […]

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Glutamatergic receptor disorders in children

What do you know about glutamatergic transmission? What kind of neuropaediatric disorders are related to glutamatergic receptor mutations? What kind of symptoms could be associated with abnormal glutamatergic transmission?     Glutamate is the most abundant excitatory neurotransmitter in the nervous system and it plays a key role in long-term potentiation (LTP). LTP is involved […]

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Cholinergic neurotransmission and the developing brain

What do you know about acetylcholine?  What about its role in the developing brain?   Are there diseases of the central nervous system due to abnormal cholinergic transmission in paediatrics? Our current knowledge about disorders of neurotransmission in children is focused on transmitters such as dopamine, serotonin or GABA. By contrast little is known about the […]

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